MedKooCat#:206092
Name:RX-3117
CAS#:865838-26-2
ChemicalFormula:C10H12FN3O4
ExactMass:257.08118
MolecularWeight:257.22
ElementalAnalysis:C,46.69;H,4.70;F,7.39;N,16.34;O,24.88
Synonym:RX3117;RX3117;RX3117;TV1360;TV1360;TV1360;fluorocyclopentenylcytosine
IUPAC/ChemicalName:4-(4-(4-fluorophenyl)-1-(3-phenylpropyl)-5-(pyridin-4-yl)-1H-imidazol-2-yl)but-3-yn-1-ol
InChiKey:QSUSKMBNZQHHPA-UHFFFAOYSA-N
InChiCode:InChI=1S/C27H24FN3O/c28-24-13-11-22(12-14-24)26-27(23-15-17-29-18-16-23)31(25(30-26)10-4-5-20-32)19-6-9-21-7-2-1-3-8-21/h1-3,7-8,11-18,32H,5-6,9,19-20H2
SMILESCode:OCCC#CC1=NC(C2=CC=C(F)C=C2)=C(C3=CC=NC=C3)N1CCCC4=CC=CC=C4
TechnicalData
AdditionalInformation
References
1:PetersGJ,SmidK,VecchiL,KathmannI,SarkisjanD,HoneywellRJ,LosekootN,OhneO,OrbachA,BlaugrundE,JeongLS,LeeYB,AhnCH,KimDJ.Metabolism,mechanismofactionandsensitivityprofileoffluorocyclopentenylcytosine(RX-3117;TV-1360).InvestNewDrugs.2013Dec;31(6):1444-57.doi:10.1007/s10637-013-0025-x.Epub2013Sep19.PubMedPMID:24048768.
