KX02 (KX2-361)
WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#:206196
CAS#:897016-26-1
Description:KX02, also known as KX2-361, is a lipophilic, orally available inhibitor of both Src kinase activity and tubulin polymerization, with potential antineoplastic activity. Upon oral administration, src/tubulin inhibitor KX02 binds to and inhibits the activity of Src kinase. This inhibits both downstream signaling and the proliferation of Src kinase-expressing tumor cells. KX02 also binds to tubulin heterodimers and inhibits microtubule polymerization, thereby disrupting microtubule formation, mitosis, and further proliferation.
Price and Availability
KX02 (KX2-361) is not in stock, but may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.
Chemical Structure
Theoretical Analysis
MedKoo Cat#: 206196Name: KX02 (KX2-361)CAS#: 897016-26-1Chemical Formula: C24H24FN3O2Exact Mass: 405.1853Molecular Weight: 405.4734Elemental Analysis: C, 71.09; H, 5.97; F, 4.69; N, 10.36; O, 7.89
Synonym:KX 2-361; KX2-361; KX-2-361;KX 2361; KX2361; KX-2361; KX 2361; KX 02; KX02; KX-02
IUPAC/Chemical Name:N-(3-fluorobenzyl)-2-(5-(4-morpholinophenyl)pyridin-2-yl)acetamide
InChi Key:CMKKPJNMYLOUCE-UHFFFAOYSA-N
InChi Code:InChI=1S/C24H24FN3O2/c25-21-3-1-2-18(14-21)16-27-24(29)15-22-7-4-20(17-26-22)19-5-8-23(9-6-19)28-10-12-30-13-11-28/h1-9,14,17H,10-13,15-16H2,(H,27,29)
SMILES Code:O=C(NCC1=CC=CC(F)=C1)CC2=NC=C(C3=CC=C(N4CCOCC4)C=C3)C=C2
