Eltrombopag free basefeatured
WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#:201240
CAS#:496775-61-2 (free base)
Description:Eltrombopag is a small-molecule, nonpeptide thrombopoietin receptor agonist with megakaryopoiesis-stimulating activity. Eltrombopag binds to and stimulates the transmembrane domain of the platelet thrombopoietin receptor (TPO-R or CD110), a member of the hematopoietin receptor superfamily. Activation of TPO-R leads to the proliferation and differentiation of cells in the megakaryocytic lineage and an increase in platelet production. Eltrombopag was approved by FDA in November 20, 2008.
Price and Availability
Eltrombopag free base purity > 98%, is in stock. The same day shipping out after order is received.
Chemical Structure
Theoretical Analysis
MedKoo Cat#: 201240Name: Eltrombopag free baseCAS#: 496775-61-2 (free base)Chemical Formula: C25H22N4O4Exact Mass: 442.16411Molecular Weight: 442.47Elemental Analysis: C, 67.86; H, 5.01; N, 12.66; O, 14.46
Related CAS #:496775-61-2 (free base)496775-62-3 (olamine)
Synonym:SB497115; SB-497115; SB 497115; SB497115GR; Eltrombopag; Brand name: PROMACTA
IUPAC/Chemical Name:3'-[2-[(2Z)-1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid
InChi Key:XDXWLKQMMKQXPV-QYQHSDTDSA-N
InChi Code:InChI=1S/C25H22N4O4/c1-14-10-11-19(12-15(14)2)29-24(31)22(16(3)28-29)27-26-21-9-5-8-20(23(21)30)17-6-4-7-18(13-17)25(32)33/h4-13,26,30H,1-3H3,(H,32,33)/b27-22-
SMILES Code:O=C(C1=CC(C2=CC=CC(N/N=C3C(C)=NN(C4=CC=C(C)C(C)=C4)C/3=O)=C2O)=CC=C1)O
Technical Data
Additional Information
Related CAS#496775-61-2 (Eltrombopag free base); 496775-62-3 (Eltrombopag olamine).
References
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