AHL196

WARNING: This product is for research use only, not for human or veterinary use.

Description:AHL196 is a FLT3 inhibitor.

Price and Availability

AHL196, purity > 98%,is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.

Chemical Structure

Theoretical Analysis

MedKoo Cat#: 406216Name: AHL196CAS#: NONEChemical Formula: C20H16F3N3O2Exact Mass: 387.11946Molecular Weight: 387.36Elemental Analysis: C, 62.01; H, 4.16; F, 14.71; N, 10.85; O, 8.26

Synonym:AHL-196; AHL196; AHL 196.

IUPAC/Chemical Name:1-(4-((2-methylpyridin-4-yl)oxy)phenyl)-3-(3-(trifluoromethyl)phenyl)urea

InChi Key:GISIPUFWENYLFB-UHFFFAOYSA-N

InChi Code:InChI=1S/C20H16F3N3O2/c1-13-11-18(9-10-24-13)28-17-7-5-15(6-8-17)25-19(27)26-16-4-2-3-14(12-16)20(21,22)23/h2-12H,1H3,(H2,25,26,27)

SMILES Code:O=C(NC1=CC=CC(C(F)(F)F)=C1)NC2=CC=C(OC3=CC(C)=NC=C3)C=C2

Technical Data

Additional Information

References

1: Weisberg E, Roesel J, Furet P, Bold G, Imbach P,Flörsheimer A, Caravatti G, Jiang J, Manley P, Ray A, Griffin JD.Antileukemic Effects of Novel First- and Second-Generation FLT3Inhibitors: Structure-Affinity Comparison. Genes Cancer. 2010Oct;1(10):1021-32. doi: 10.1177/1947601910396505. PubMed PMID: 21779428;PubMed Central PMCID: PMC3092267.