Debio-1347featured
WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#:206156
CAS#:1265229-25-1
Description:Debio-1347, also known as FF284 and CH5183284, is an orally bioavailable inhibitor of the fibroblast growth factor receptor subtypes 1 (FGFR-1), 2 (FGFR-2) and 3 (FGFR-3), with potential antineoplastic activity. FGFR inhibitor debio 1347 binds to and inhibits FGFR-1, -2, and -3, which result in the inhibition of FGFR-mediated signal transduction pathways. This leads to the inhibition of both tumor cell proliferation and angiogenesis, and causes cell death in FGFR-overexpressing tumor cells.
Price and Availability
Debio-1347, purity > 98%, is in stock. The same day shipping after order is received.
Chemical Structure
Theoretical Analysis
MedKoo Cat#: 206156Name: Debio-1347CAS#: 1265229-25-1Chemical Formula: C20H16N6OExact Mass: 356.13856Molecular Weight: 356.38Elemental Analysis: C, 67.40; H, 4.53; N, 23.58; O, 4.49
Related CAS #:1265229-25-11265231-80-8
Synonym:Debio-1347; Debio 1347; Debio1347; CH5183284; CH 5183284; CH-5183284; FF284; FF-284; FF 284.
IUPAC/Chemical Name:(5-amino-1-(2-methyl-1H-benzo[d]imidazol-6-yl)-1H-pyrazol-4-yl)(1H-indol-2-yl)methanone
InChi Key:BEMNJULZEQTDJY-UHFFFAOYSA-N
InChi Code:InChI=1S/C20H16N6O/c1-11-23-16-7-6-13(9-17(16)24-11)26-20(21)14(10-22-26)19(27)18-8-12-4-2-3-5-15(12)25-18/h2-10,25H,21H2,1H3,(H,23,24)
SMILES Code:O=C(C1=C(N)N(C2=CC=C3C(NC(C)=N3)=C2)N=C1)C(N4)=CC5=C4C=CC=C5
