CNX-774featured
WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#:406107
CAS#:1202759-32-7
Description:CNX-774 is a potent Btk inhibitor (IC50 < 1 nM). Recently Bruton's tyrosine kinase (BTK) , a crucial terminal kinase enzyme in the B-cell antigen receptor (BCR) signaling pathway, has emerged as an attractive target for therapeutic intervention in human malignancies and autoimmune disorders.
Price and Availability
CNX-774 purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.
Chemical Structure
Theoretical Analysis
MedKoo Cat#: 406107Name: CNX-774CAS#: 1202759-32-7Chemical Formula: C26H22FN7O3Exact Mass: 499.17682Molecular Weight: 499.49638Elemental Analysis: C, 62.52; H, 4.44; F, 3.80; N, 19.63; O, 9.61
Synonym:CNX774; CNX 774; CNX-774.
IUPAC/Chemical Name:4-(4-((4-((3-acrylamidophenyl)amino)-5-fluoropyrimidin-2-yl)amino)phenoxy)-N-methylpicolinamide
InChi Key:VVLHQJDAUIPZFH-UHFFFAOYSA-N
InChi Code:InChI=1S/C26H22FN7O3/c1-3-23(35)31-17-5-4-6-18(13-17)32-24-21(27)15-30-26(34-24)33-16-7-9-19(10-8-16)37-20-11-12-29-22(14-20)25(36)28-2/h3-15H,1H2,2H3,(H,28,36)(H,31,35)(H2,30,32,33,34)
SMILES Code:O=C(NC)C1=NC=CC(OC2=CC=C(NC3=NC=C(F)C(NC4=CC=CC(NC(C=C)=O)=C4)=N3)C=C2)=C1
